Structure of DNA Replication Protein - It is Complex
February 17, 2017
The following article discusses research of the 3D structure of a key protein that helps damaged DNA be repaired. The article states, "a team of investigators from multiple institutions, who worked for more than two years to decipher the unusual configuration of the protein PrimPol, whose function was discovered in 2013. PrimPol is used in cells when normal repair proteins encounter damaged sections of DNA, often caused by anticancer chemotherapy drugs. The protein can skip over the damage to rescue DNA replication".
The article goes on to say, "DNA damage happens constantly -- more than 100,000 events occur in every human cell each day".
Finally, the article states, "The basic steps involved in DNA replication are known. The first step involves unzipping the intertwined double helix DNA structure, creating a "Y" shape known as a replication fork. These two strands act as templates for making the new DNA strands. A short piece of RNA known as a primer (produced by a primase enzyme) acts as the starting point for the synthesis of new DNA." and "It had been believed that DNA polymerase and primase activities in human cells were the province of separate enzymes. Then PrimPol was discovered, and the understanding of DNA replication changed dramatically. PrimPol was found to be capable of both restarting and performing DNA synthesis after DNA replication stalls".
In summary, researcher found a very complex protein, the PrimPol, which is multi-functional. In addition, the article touches on the complex DNA replication process and the fact that effective repair mechanisms must be in place since DNA damage occurs at high rates. This should lead an evolutionist to ask the question of "How did DNA survive before the repair mechanisms evolved?". The answer is it couldn't have based on the observable science and the advanced and efficient repair mechanisms must have been functional from the beginning. This is impossible with the theory of evolution, but lines up well with what is described in the Bible. That, in the beginning, we were created perfect and fully functional.
Tour the links in the "More" section of this site to learn more about why evolution is not true and the observable science points towards a perfect original creation by God.
Click the image below to read a scientific article to support this statement.
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